Ratios of mRNA transcript abundance between sample types are measures of biological activity. These measurements of differential gene expression are important to underpin new biological hypotheses and ...

We needed a way of representing prior biological knowledge in the computer, so we developed a logical formalism to model cellular metabolism that captures the key relationship between protein-coding ...

All pharmaceutical products are formulated to specific dosage forms for drugs to be effectively delivered to patients. Typical pharmaceutical dosage forms include oral tablets, capsules, solutions, ...

I STARTED collecting examples of bizarre experiments years ago while in graduate school studying the history of science. I confess I had no profound intellectual motive; I simply found them ...

Formulation development can involve several complex technical challenges, but an approach incorporating design of experiments can help address these difficulties. All pharmaceutical drug products are ...